| ncRNA name | EpCAM siRNA |
| ncRNA Category | siRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RB cell line WERI-RB1; primary RB tumor cells; breast cancer cell line MCF7 |
| Methods | siRNA transfection, qRT-PCR, Northern and Western blot, immunohistochemistry, MTT assay, xenograft, Protein array |
| Expression pattern | associated |
| Functional description | Our results revealed that EpCAM aptamer-siEpCAM chimera (EpApt-siEp) potentially eradicated EpCAM positive cancer cells through CSC marker suppression and apoptosis, while sparing normal EpCAM negative adjacent cells. |
| PubMed ID | 26176230 |
| Year | 2015 |
| Title | EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer. |
| Drug-related ncRNA | NO |
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